Most hog farms successfully stamp out mycoplasma pneumonia when they work with their veterinarian to eliminate the disease. The challenge is preventing reinfection.
If the herds remain negative after the first 8 months, they became reinfected at a much slower rate over a much longer time than the herds turning positive in 8 months, reported Paul Yeske, DVM, Swine Vet Center, St. Peter, Minnesota.
Yeske and his colleagues looked at all the clinic’s herds taken through a mycoplasma-elimination program. They rated the success of each effort and plotted over time when the herds turned positive, which they called the decay rate.
81% elimination success
They noted a distinct difference between herds that used a closure plan with medication (water medication for sows and injection to piglets) for the elimination versus just medication (injection of both sows and piglets).
“On herds using a closure and medication plan, we were 81% successful,” Yeske said. “In herds with medication and no closure, we were at 62% success.”
The clinic’s protocol for whole-herd elimination required all pigs on the farm to receive a vaccine injection followed with a second dose 2 weeks later. In elimination with no herd closure, animals that become infected with mycoplasma can shed the organism for up to 8 months.
“I believe what happens with no herd closure is some of the herds decay rapidly because we never got mycoplasma totally eliminated,” Yeske said. “If they make it to 8 months, the pigs were done shedding and the herd was able to stay negative going forward.”
More negative herds in future
“Mycoplasma elimination is one program that’s been widely done in a relatively high number of herds and has been successful. I think we will see more and more people adopt elimination and see more herds go to mycoplasma-negative pigs because of the economic benefits with grow-finish production,” he explained.
“The good thing with mycoplasma is we have the tools to eliminate and successfully keep it out of our herds for a long time.”
The Seneca Valley virus (SVV) is proving to be something of a test case for swine producers’ and veterinarians’ preparedness for foreign animal diseases (FADs).
While SVV is not an FAD, nor does it pose a harsh economic penalty for infected herds, the virus does produce lesions on the pig’s snout, feet and coronary bands that are indistinguishable from FADs, particularly foot-and-mouth disease.
Last summer, Jake Schwartz, DVM, Swine Vet Center, St. Peter, Minnesota, spent time investigating SVV outbreaks in Nebraska. In less than a month, a single packing plant required 124 animal-disease investigations because market hogs started showing up with lesions and vesicles. The good news was the pigs tested negative for FADs; the bad news — they tested positive for SVV.
“There were zero reports of lesions at the originating pig sites, which involved five different states — Kansas, Minnesota, Iowa, Nebraska and South Dakota,” Schwartz told Pig Health Today. “So, either the pigs at the site were never infected or they were infected and the lesions healed relatively fast and we all missed it.”
There is much still to be learned about the virus — the transmission route, infectious period, risk factors, biosecurity effectiveness and more. But hog transport trailers are one suspected route of bringing SVV back to the farm. The linkage has been evident with market hogs as well as some sow-herd cases.
“We learned with the porcine epidemic diarrhea virus (PEDV) that it was not uncommon to have trailers arrive at the packing plant negative for PEDV. But when the trailer left the plant it was positive,” Schwartz said. “Then we drag the virus back to the farm.”
Although the exact steps to prevent SVV from entering a production site have not been scientifically confirmed, for now the best defense is to step up truck and trailer biosecurity protocols. This means wash, disinfect and dry the trailer between every hog transport.
“We don’t know if the thermos-assisted drying process is able to kill SVV, but we know it works quite well for PED and the porcine reproductive and respiratory syndrome virus,” he added. That essentially involves heating the trailer to a surface temperature of 150° F to 160° F for a period of time, say 30 minutes.
“As an industry, we talk about being prepared for an FAD; we talk about vaccine banks and many other strategies,” Schwartz said. “But part of that discussion needs to include how we manage our hog trailers in a way that would slow down or reduce the contamination risk in the event we did get an FAD in the US.”
The spike in sow-mortality rates in recent years has everyone in the US pork industry searching for answers. Don’t expect any simple solutions, however. In most cases, multiple factors lead to mortality or declines in sow performance, according to Paul Yeske, DVM, Swine Vet Center, St. Peter, Minnesota.
“Like many different things in the industry, it’s multi-factorial…not just one thing,” he told Pig Health Today.
Not all farms experience high mortality rates. Yeske said he sees a lot of variability among sow herds, and they try to understand why there’s a difference.
Expansion drives higher selection rates
One reason sow mortality increased relates to herd expansion. “As we’ve seen more expansion, we tend to have higher selection rates and sometimes end up with more mortality,” Yeske said.
“Ideally, we’d have a selection rate of 50% to 60%, and sometimes we end up…in the 70% to 80% range,” he explained. “Some of those animals probably shouldn’t have come to the barn to begin with.
“Make sure you bring enough of the animals in to allow for proper selection and not take what’s available,” he added.
In units with internal multiplication, Yeske recommended maintaining a purebred herd large enough to produce the needed replacement gilts. If gilts are outsourced, bring in enough animals for cover selection.
He also suggested making sure sow herds are sized properly. “Sometimes we just have to stand back and make sure the right animals come into the farm,” he said. “If the animal is structurally questionable, it’s going to be more difficult for that animal to stay in the herd.”
Lameness is a leading contributor to higher sow-mortality rates, along with prolapses. “Some research work is actively being done to try and understand what’s going on. We know it’s occurring; we just don’t know exactly why,” he added.
Maintain body condition
Another cause of sow mortality relates to higher production rates and body condition.
“We’re seeing higher levels of [sow] productivity than we’ve ever seen,” Yeske continued. “Are we meeting the needs of this higher-producing animal?” Research on sow diets dates back a number of years when production rates were lower, he noted.
Good body condition is essential for keeping sows in the herd. “If we get the animals into the herd, keep them in the right body condition,” Yeske said. “That’s going to add to their longevity.
“If the animals are yo-yoing a lot on weight, it’s going to add more stress and more challenges. Try to keep them very uniform and consistent on weight.”
Match health status
It’s important to remember that gilts entering a herd are stressed as they begin to develop herd immunity. Producers need to properly acclimate gilts to diseases they may face.
“Understand the health status of the animal coming in, manage it to match your herd and then identify the problems as they show up,” Yeske advised.
“If we don’t get that done right, that just adds more stress to those young-parity animals and ends up having them exit the system faster than they should.”
Fast intervention
Speed is also critical. “Herds that have fast intervention on problem animals tend to have the lowest mortality,” he said.
“Make sure you do individual pig care every day. Go out and check every animal every day. Make sure the animal is getting up and good on all four legs. Make sure the animal is eating and [there are] no other signs of any health problems,” he added.
By Paul Yeske, DVM Swine Vet Center St. Peter, Minnesota
Research shows that if more piglets are positive for Mycoplasma hyopneumoniae (M. hyo) at weaning, there will be more problems in finishers, with decreased average daily gain, increased mortality and poor feed conversion.1 There will be a lower percentage of pigs sent to the primary market as well as higher treatment costs.
The costs of M. hyo can really add up. When actual production numbers from 2007 to 2015 are plugged into an economic model, the cost is $4.99 per pig.2 Data from other farm systems indicate it’s $2.85 per pig.3
To reduce the amount of downstream disease in pigs, we need to reduce the amount of M. hyo shedding. This begins with proper acclimatization of gilts going into the sow herd, which is a challenge.
Negative gilts present challenges
Historically, most replacement gilts were born into positive herds, or they were raised internally in the herd and were infected early in life. They had plenty of time for shedding to minimize before farrowing, which helped keep herds stable for M. hyo. By stable, I mean a low percentage of weaning-age pigs are positive for the pathogen within the respiratory tract.
Today, most replacement gilts are negative for M. hyo and aren’t acclimatized until they get to the sow farm. Therefore, the first challenge is getting them infected within a reasonable time frame.
Gilts need to be brought in at a young enough age so there’s enough time following infection for M. hyo shedding to decline. This is critical whether you want to stabilize a positive sow farm and reduce the impact of clinical disease in the finishing phase or if your goal is herd closure and M. hyo elimination.
Ideally, negative gilts would be infected by 84 days of age. Figure 1 demonstrates the time needed to reduce shedding in farrowing gilts and their piglets.
Figure 1. Gilt Mycoplasma hyopneumoniae exposure timeline
Gilt-exposure methods
There are several methods of exposing negative gilts:
Use seeder animals, an approach that’s been utilized in the industry for a long time. It works well if the right animals are used and there’s plenty of time — but it can also be difficult.To achieve a shorter time for infection, such as 30 days, six seeders for every four naïve gilts is needed to be 100% successful. However, if the infection in the seeders dies out, it can be difficult to get the acclimatization program restarted. The result can be problems with M. hyo in finishers and lost performance during the process, and it may take time to re-establish herd stability.
Intratracheal inoculation is another way to acclimatize naïve gilts and has been explored in the research arena. I wouldn’t recommend this method because it’s labor intensive and it can pose a danger to staff since restraint of gilts is necessary.
Aerosol inoculation is new technology that’s been used in other species for vaccination and may be a possibility for hyo acclimatization of gilts. It’s less labor intensive than intratracheal inoculation and animals don’t have to be restrained. There are some technical steps required. For example, it has to be done in an area with small air space. If you want to consider this approach, it’s imperative to work with your herd veterinarian so all the technical details are addressed.
One of the keys to successful acclimatization is having a good diagnostic protocol to confirm that gilts have in fact been properly exposed. Toward this end, testing every group of exposed naïve gilts is key, whether your goal is M. hyo herd stabilization or elimination.
Considering elimination?
M. hyo elimination is possible using a combination of herd closure, vaccination of the breeding herd and medicating of the breeding herd as well as piglets. Infected piglets also can be treated individually with an injectable antibiotic to help reduce the impact of the disease.
Elimination is recommended when it becomes a struggle to get gilts exposed on a consistent basis, for herds in a filter project and when producers simply become tired of dealing with costly M. hyo clinical problems.
If you’re considering M. hyo elimination, one of the first questions to ask is whether it really will be worthwhile. This might not be possible for farms located in pig-dense areas where reinfection is a strong possibility. However, when we followed 100 sites in pig-dense areas throughout two seasonal periods, we found only 6% of the sites were positive for M. hyo from lateral-source introduction.
Summing up
Proper gilt acclimatization is key to successful herd stabilization and M. hyo management. This applies whether your goal is to stabilize the herd and minimize the load of M. hyo in weaned pigs or to eliminate M. hyo.
A good diagnostic plan is essential. Every group of gilts that enters the herd must be checked after exposure to ensure proper acclimatization. Unfortunately, it takes time, especially in herds receiving adult replacements. Acclimatization of gilts is also more challenging today because most replacement gilts are M. hyo-negative.
Lateral transmission does occur, but it’s not very frequent. If you are having a problem controlling M. hyo in a herd, it’s likely a problem originating from the source sow herd and not the geographic area.
You’ll have better results managing M. hyo if you work with your herd veterinarian to develop an individualized plan.
Editor’s note: The opinions and recommendations presented in this article are the author’s and are not necessarily shared by the editors of Pig Health Today or its sponsor.
1. Schwartz M. Cost of M. Hyopneumoniae in growing pigs. 2015 Allen D Leman conference.
2. Linhares D. A field study on economics of Mycoplasma hyopneumoniae elimination. 2017 Allen D Leman conference.
3. Yeske P. Mycoplasma hyopneumoniae Elimination. Proceedings from AASV annual meeting. 2016:376-381.
Ross Kiehne, DVM, practices what he calls “precision animal health.”
“I’m only going to provide the vaccine or antibiotic that’s right for the pig at that time in its life to make it as healthy as possible,” the swine veterinarian says in a video produced as part of the Vets on Call series.
Growing up on the family farm, Kiehne says he witnessed the high level of livestock care shown by his father, who taught his son that the farmer is “the guardian of the welfare of the animals first and foremost.”
“We have to speak for them because they can’t speak for themselves,” stressed Kiehne, with the Swine Vet Center in St. Peter, Minn. “I take that pretty seriously.”
Visiting a farrowing room, Kiehne focuses on the health and welfare of the sow and her recently born piglets.
“We want to find the right environment for them,” he says. “These sows have feed and water at all times; the sow is contained; it’s safe for the piglets to move around her all the time in a warm, dry environment.”
Even though he’s not in every swine barn every day, he can help the people who are by showing them what to look for and how to give the best care possible to the animals.
“Half of my job as a veterinarian is devoted to training the people who will take care of the pigs on a daily basis.”
And that involves treating sick animals. Kiehne says the welfare of the animal is much better if sick animals are treated with the proper antibiotic until they recover.
“We want everyone to understand where their pork comes from; this is how it’s made and we feel pretty good about it,” he says.
Vets on Call is a video series presented by Zoetis to showcase the important roles veterinarians play in food-animal production.
With the recent outbreaks and spread of African Swine Fever (ASF) in Europe and Asia there has been heightened attention to biosecurity in the U.S. pork industry. Efforts are being made on an industry level to reduce risk to our industry from international travelers and feed ingredients being brought into the U.S.
ASF is a double-edged sword for the U. S. industry. It is creating tremendous (potential) market opportunities for U. S. pork. China is the world’s largest producer and consumer of pork. With estimates of at least 9 million sows lost in China (~1.5X the U.S. industry’s entire sow population), there will continue to be a hole in their domestic production for a long time to come. And reports would indicate that they are going to have a difficult time rebuilding their industry. The down side to ASF is that if the U.S. would get it, our exports would stop immediately. This would obviously be devastating for pork prices. And if the virus is detected in the U.S. , all pig movements would be stopped for at least 72 hours while officials work to determine the extent of the infection.
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This is where the Secure Pork Supply (SPS) Plan comes into play. The SPS plan is essentially a detailed biosecurity plan for each of your production sites that you create with your veterinarian and submit to the Board of Animal Health for approval. It does take some time but would be well worth it in the case of an emergency shutdown since SPS herds will be the first allowed to resume normal operations. More information about SPS and also foreign animal diseases can be found at the following website or you can contact your SVC Veterinarian.
New PQA Plus 4.0
SVC veterinarians were recently certified as trainers of the new PQA Plus 4.0 program. Starting in June of 2019 this new version of the PQA program will be used for both individual certifications and site assessments.
The individual certification and site assessment both need to be renewed every 3 years. The biggest change with the new program is the individual certification process. This now involves watching 90 minutes of interactive videos with your trainer so make sure to allow for enough time when planning to re-certify. There are different video options for people being certified for the 1st time and people that are going through a re-certification.
Technically the PQA program is still a voluntary program but all major packers require suppliers to be certified and sites to be assessed.
Hemorrhagic Bowel Syndrome (HBS)
Hemorrhagic Bowel Syndrome (HBS) causes sudden death in finishing barns.
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The cause is not known for sure but an overgrowth of a Clostridium bacteria is one possible cause. Even high health flows of pigs are susceptible to this syndrome. Normally it is a large, healthy pig that is found dead from HBS making it a very frustrating and expensive problem. Some genetic lines appear to be more suscep-tible to HBS. Many different nutritional and management strategies have been tried to prevent HBS deads, including:
Fiber is generally a good thing for a healthy gut and HBS is no exception. Some research would indicate that maintaining fiber in finishing diets will reduce HBS deads. DDGs are the most common source of fiber but in some cases other options need to be investigated.
Disruptions in feed intake appear to lead to more HBS deads. This could be from feed outages, health challenges, or temperature/weather stress.
Stir fans and misters in finishing barns help keep pigs cool during hot weather which can lead to better average daily gain and fewer HBS deads.
There are barns where all of the HBS deads occur at the curtain end of the barn which would suggest that pigs that are not comfortable don’t eat consistently.
Some would also recommend running feeders a bit looser to ensure consistent feed intake.
Overstocking can also restrict feed intake.
Different feed medication programs have been tried to control this issue with results that have not been consistent.
Water treatments may help alter the microbes in the gut when an outbreak of HBS deads happens in a barn. Things such as apple cider vinegar, bleach, and antibiotics have been tried.
Congratulations Dr. Chris and Brooke Sievers!
Swine Vet Center extends its warmest congratulations to Dr. Chris and Brooke Sievers on the birth of their son. Gavin Christopher arrived on June 16 at 5:26 a.m. (What a wonderful Father’s Day gift!) Gavin weighed in at 7lbs, 7oz. Both baby and mom are doing great.
Swine Vet Center wishes Dr. Chris and Brooke much joy and happiness in this new chapter in their lives!
No portion of this newsletter may be used/copied without written consent of Swine Vet Center
Eliminating porcine reproductive and respiratory syndrome virus (PRRSV) from pigs might not yet be possible, but monitoring tools could help refine a herd’s PRRSV stability.
A new variant of the porcine reproductive and respiratory syndrome virus 1-4-4 L1C strain is challenging veterinarians, diagnosticians and swine herds in the upper Midwest.
TOOLBOX, Issue 23: Noel Garbes DVM, senior technical services veterinarian, Zoetis, recently talked with editors of Pig Health Today about monitoring swine herds for PCV2.
The system used to classify breeding herds according to their PRRSV status has long helped swine veterinarians around the world to track the pathogen’s progress.
A special report from Pig Health Today, “Integrated Flu Management: New Strategies for Control,” reports on key presentations by experts in influenza A virus in swine (IAV-S) and features highlights of a roundtable involving swine practitioners.
TOOLBOX, Issue 22: David A. Baumert, DVM, Senior Area Veterinarian, Pork Technical Services, Zoetis, recently talked with editors of Pig Health Today about Mycoplasma elimination vs control.
Colostrum is vital to piglet survival but managing intake may benefit from some fresh thinking, according to Kara Stewart, associate professor of animal science at Purdue University.
DISCOVERIES, Issue 22: A robust body of research explains the efficacy of Excede® for Swine (ceftiofur crystalline free acid) against four of the bacterial pathogens associated with swine respiratory disease.
Pig health and performance begin with the sow, which is why it’s critical for caregivers and production managers to evaluate each sow’s health, body condition, comfort, behavior and well-being as part of their daily routine. “By training workers, we can help them reduce sow mortality rates and culls, improve sow performance, stabilize the health status […]
DISCOVERIES, Issue 20: Pigs with swine respiratory disease due to Actinobacillus pleuropneumoniae were treated with Excede® for Swine (ceftiofur crystallinefree acid) or enrofloxacin in a comparative challenge study.
DISCOVERIES, Issue 24: An analysis of three similar injectable antibiotics used for swine respiratory disease pathogens demonstrates that resuspension times can differ substantially.
US producers and veterinarians have seen an influx of different types of influenza viruses in the last 10 to 15 years, and that is a major reason why influenza is more difficult to control.
Water doesn’t get the attention it deserves because it is abundant, easy to access and inexpensive, but that will change in the future, said John Patience, PhD, professor at Iowa State University.
DISCOVERIES, Issue 18: Obtaining cycle threshold (Ct) values based on processing fluids provides a practical way to identify neonatal pigs at risk for nursery mortality associated with PRRS and can help determine when vaccination is worthwhile.
Multi-disciplinary collaboration by academia, industry partners and the veterinary community is improving the diagnostics for and management of S. suis.
DISCOVERIES, Issue 21: A recent analysis of porcine circovirus type 2 (PCV2) genetic sequences shows that up to 25% of field strains are recombinants of diverse genotypes, highlighting the importance of broad protection when selecting a PCV2 vaccine.
According to research, swine influenza A viruses have become more complicated in recent years. There is a great deal of diversity within the influenza virus.
The “Five Freedoms” have been the foundation for establishing sound animal welfare practices since they were developed in 1965. Now, more than 50 years later, researchers have additional tools and technologies to take that basic knowledge a step further.
DISCOVERIES, Issue 19: PRRS has been described as one of the most important swine diseases of the last half-century. An estimated 20% to 25% of herds are still affected, and the syndrome remains the US swine industry’s most costly disease.
In the end, raising hogs is about producing pork, and continuous success depends on building customers’ trust, listening to expectations and meeting their needs.
Biosecurity protocols are critical to keeping the US hog herd healthy, and one of the regular tasks is to disinfect a wide range of supplies entering the farm, but how effective are those protocols?
A romanticized view of the veterinary profession, gleaned from sources like the famous Brit, James Herriot’s novel “All Creatures Great and Small,” doesn’t always mesh with the reality.
Pain management for pigs has always been a challenge, partly because it’s difficult to measure levels of pain and partly because there are no FDA-approved drugs labeled for pain management in pigs.
Piglet processing fluids have been shown to be a practical, time-efficient and affordable diagnostic tool for PRRS, and some indications suggest that PCV2 offers promise as well.
US pork producers should strive to produce influenza-negative pigs if they want to see the benefits of increased productivity, reduced secondary infections and antibiotic use, reduced influenza dissemination, decreased influenza diversity and reduced risk of zoonotic infections.
The farrowing room is a demanding place — one that needs to accommodate the divergent needs of a 500+-pound sow and her 10, 15 or 20 piglets weighing anywhere from 1.5 to 3 pounds.
COVID-19’s global-altering tentacles reached the 2020 Allen D. Leman Swine Conference scheduled Sept. 19-22. This year’s conference will be held virtually.
The first case of Streptococcus equi subsp. zooepidemicus (Strep. zoo) was identified in the US pig population last fall, and it’s not an organism to be taken lightly.
Sow mortality has been on the rise in the US pork industry, reaching upwards of 15% in many sow-production systems, said Ashley Johnson, DVM, technical services veterinarian with Zoetis.
Whether the issue is an emerging disease such as porcine epidemic diarrhea or the threat of African swine fever, being prepared is key to minimizing the potential impact on the US swine herd and expediting the recovery.
Veterinarians deal with stress under the best circumstances. But in this time of difficult decisions for pork producers and those who service them due to COVID-19, maintaining mental health is even more of a concern.
For both the sow and piglet, an animal that does not perform to its potential or falls behind its counterparts will negatively impact the sow farm’s productivity and profitability.
Clinical problems in swine due to antimicrobial-resistant infections are rare. In fact, patterns of resistance in swine have been stable for a long time.
Many sow farms have undergone M. hyo elimination within their breeding herd, which makes it critical to understand the potential transmission risk from boar studs.
Few things remain the same for long on a hog farm. By the very nature of today’s production system, pigs are continuously moving on or off a site. One thing that remains constant is Strep suis.
Effective PCV2 control relies on vaccination of healthy pigs before they become infected. This goal cannot be accomplished in unstable herds whose sows give birth to viremic pigs.
Porcine circovirus type 2 is the principal etiological agent of porcine circovirus associated disease (PCVAD), which can cost producers an estimated $3 to $4 per pig.
Streptococcus suis (Strep suis) is becoming more prevalent and more complex in US swine herds. The coccoid-shaped, Gram-positive bacterium is also a zoonotic disease, capable of transmission from pigs to humans.
When it comes to porcine reproductive and respiratory virus it’s important for the veterinarian and farm personnel to know the health status of a herd or barn.